Hannah & Otto follows a day in the life of the two titular characters; strangers who move through their daily routines of exercise, the morning commute, working, and meeting with friends. Told in a palindromic style, the film revolves around a chance meeting on the street where the two characters bump into each other and are instantly drawn to one another. But while the duties of everyday life pull them apart, the captivation of that moment remains in their minds and fate conspires to bring them back together.